Cross susceptibility and absence of cross resistance to cefotetan and cefoxitin

Author:

Barry A L,Jones R N

Abstract

Tests with 2,713 bacterial isolates (members of the family Enterobacteriaceae and gram-positive cocci) from 14 laboratories compared cefoxitin MICs with cefotetan MICs. Strains that were susceptible to cefoxitin could be assumed to be susceptible to cefotetan. Over half of the cefoxitin-resistant isolates of the Enterobacteriaceae were susceptible to cefotetan.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference5 articles.

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2. Antimicrobial activity of cefmetazole (CS-1170) and recommendations for susceptibility testing by disk diffusion, dilution, and anaerobic methods;Jones R. N.;J. Clin. Microbiol.,1986

3. Antimicrobial activity, beta-lactamase stability and beta-lactamase inhibition of cefotetan and other 7-alpha-methoxy beta-lactam antimicrobials;Jones R. N.;Diagn. Microbiol. Infect. Dis.,1983

4. National Committee for Clinical Laboratory Standards. 1985. Approved standard M7-A. Standard methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically. National Committee for Clinical Laboratory Standards Villanova Pa.

5. Cefotetan pharmacokinetics in volunteers with various degrees of renal function;Smith B. R.;Antimicrob. Agents Chemother.,1986

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