Comparative Genomic Analysis of Two Multidrug-Resistant Clinical Isolates of ST395 Epidemic Strain of Pseudomonas aeruginosa Obtained 12 Years Apart-Reference-Cited by-同舟云学术

Comparative Genomic Analysis of Two Multidrug-Resistant Clinical Isolates of ST395 Epidemic Strain of Pseudomonas aeruginosa Obtained 12 Years Apart

Published:2014-06-26 Issue:3 Volume:2 Page:
ISSN:2169-8287
Container-title:Genome Announcements
language:en
Short-container-title:Genome Announc

Author:

Valot Benoit¹,Rohmer Laurence²,Jacobs Michael A.²,Miller Samuel I.³,Bertrand Xavier¹⁴⁵,Hocquet Didier¹⁴⁵

Affiliation:

1. UMR 6249 CNRS Chrono-environnement, Université de Franche-Comté, Besançon, France

2. Department of Microbiology, University of Washington, Seattle, Washington, USA

3. Department of Genome Sciences, Immunology, Medicine, University of Washington, Seattle, Washington, USA

4. Infection Control Department, University Hospital, Besançon, France

5. Biological Resources Center–Ferdinand Cabanne, University Hospital, Besançon, France

Abstract

ABSTRACT Pseudomonas aeruginosa can cause large and prolonged outbreaks in hospitals. We have sequenced and annotated the genomes of two multidrug-resistant P. aeruginosa isolates from the same strain obtained 12 years apart from different patients. Genomic analysis provided insight on the genes acquired and lost by P. aeruginosa during its spread.

Publisher

American Society for Microbiology

Subject

Genetics,Molecular Biology

Link

https://journals.asm.org/doi/pdf/10.1128/genomeA.00515-14

Reference8 articles.

1. Molecular Characterization of an Epidemic Clone of Panantibiotic-Resistant Pseudomonas aeruginosa

2. Large Outbreak in a Surgical Intensive Care Unit of Colonization or Infection withPseudomonas aeruginosathat Overexpressed an Active Efflux Pump

3. Genetic and Phenotypic Variations of a Resistant Pseudomonas aeruginosa Epidemic Clone

4. Velvet: Algorithms for de novo short read assembly using de Bruijn graphs

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