Outbreak of H7N8 Low Pathogenic Avian Influenza in Commercial Turkeys with Spontaneous Mutation to Highly Pathogenic Avian Influenza

Author:

Killian Mary Lea1,Kim-Torchetti Mia1,Hines Nichole1,Yingst Sam2,DeLiberto Thomas3,Lee Dong-Hun4

Affiliation:

1. National Veterinary Services Laboratories, Veterinary Services, U.S. Department of Agriculture (USDA), Ames, Iowa, USA

2. Animal Disease Diagnostic Laboratory, Purdue University, West Lafayette, Indiana, USA

3. USDA Wildlife Services National Wildlife Research Center, Fort Collins, Colorado, USA

4. USDA Agriculture Research Service, Southeast Poultry Research Laboratory, Athens, Georgia, USA

Abstract

ABSTRACT Highly pathogenic avian influenza (HPAI) subtype H7N8 was detected in commercial turkeys in January 2016. Control zone surveillance discovered a progenitor low pathogenic avian influenza (LPAI) virus in surrounding turkey flocks. Data analysis supports a single LPAI virus introduction followed by spontaneous mutation to HPAI on a single premises.

Publisher

American Society for Microbiology

Subject

Genetics,Molecular Biology

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