New Player in Endosomal Trafficking: Differential Roles of Smad Anchor for Receptor Activation (SARA) Protein

Author:

Rozés-Salvador Victoria1234,Siri Sebastian O.123,Musri Melina M.123,Conde Cecilia123

Affiliation:

1. Universidad Nacional de Córdoba (UNC), Ciudad Universitaria, Córdoba, Argentina

2. Instituto Mercedes y Martín Ferreyra (INIMEC-CONICET), Córdoba, Argentina

3. Instituto Universitario Ciencias Biomédicas de Córdoba (IUCBC), Córdoba, Argentina

4. Instituto A.P. de Ciencias Básicas y Aplicadas, Universidad Nacional de Villa María (UNVM), Ciudad Universitaria, Villa María, Argentina

Abstract

The development and maintenance of multicellular organisms require specialized coordination between external cellular signals and the proteins receiving stimuli and regulating responses. A critical role in the proper functioning of these processes is played by endosomal trafficking, which enables the transport of proteins to targeted sites as well as their return to the plasma membrane through its essential components, the endosomes.

Funder

MINCyT | ANPCyT | Fondo para la Investigación Científica y Tecnológica

Fundación Alberto J. Roemmers

Publisher

American Society for Microbiology

Subject

Cell Biology,Molecular Biology

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