Whole-Genome Sequencing in Epidemiology of Campylobacter jejuni Infections-Reference-Cited by-同舟云学术

Whole-Genome Sequencing in Epidemiology of Campylobacter jejuni Infections

Published:2017-05 Issue:5 Volume:55 Page:1269-1275
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Llarena Ann-Katrin¹,Taboada Eduardo²^ORCID,Rossi Mirko¹

Affiliation:

1. Department of Food Hygiene and Environmental Health, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland

2. National Microbiology Laboratory at Lethbridge, Animal Diseases Research Institute, Public Health Agency of Canada, Lethbridge, Alberta, Canada

Abstract

ABSTRACT This review describes the current state of knowledge regarding the application of whole-genome sequencing (WGS) in the epidemiology of Campylobacter jejuni , the leading cause of bacterial gastroenteritis worldwide. We describe how WGS has increased our understanding of the evolutionary and epidemiological dynamics of this pathogen and how WGS has the potential to improve surveillance and outbreak detection. We have identified hurdles to the full implementation of WGS in public health settings. Despite these challenges, we think that ample evidence is available to support the benefits of integrating WGS into the routine monitoring of C. jejuni infections and outbreak investigations.

Funder

European Food Safety Agency [Italy]

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00017-17

Reference31 articles.

1. A Framework for Assessing the Concordance of Molecular Typing Methods and the True Strain Phylogeny of Campylobacter jejuni and C. coli Using Draft Genome Sequence Data

2. Routine Use of Microbial Whole Genome Sequencing in Diagnostic and Public Health Microbiology

3. Prospective use of whole genome sequencing (WGS) detected a multi-country outbreak of Salmonella Enteritidis