Comparison of the Quantitative DiaSorin Liaison Antigen Test to Reverse Transcription-PCR for the Diagnosis of COVID-19 in Symptomatic and Asymptomatic Outpatients-Reference-Cited by-同舟云学术

Comparison of the Quantitative DiaSorin Liaison Antigen Test to Reverse Transcription-PCR for the Diagnosis of COVID-19 in Symptomatic and Asymptomatic Outpatients

Published:2021-06-18 Issue:7 Volume:59 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Lefever Stefanie¹^ORCID,Indevuyst Christophe²,Cuypers Lize¹,Dewaele Klaas¹,Yin Nicolas³^ORCID,Cotton Frédéric⁴,Padalko Elizaveta⁵,Oyaert Matthijs⁶,Descy Julie⁷,Cavalier Etienne⁸,Van Ranst Marc¹⁹,André Emmanuel¹⁹,Lagrou Katrien¹⁹,Vermeersch Pieter¹¹⁰^ORCID

Affiliation:

1. Clinical Department of Laboratory Medicine and National Reference Center for Respiratory Pathogens, University Hospitals Leuven, Leuven, Belgium

2. Clinical Laboratory, Medisch Centrum Huisartsen, Leuven, Belgium

3. Department of Microbiology, LHUB-ULB, Université Libre de Bruxelles, Brussels, Belgium

4. Department of Clinical Chemistry, LHUB-ULB, Université Libre de Bruxelles, Brussels, Belgium

5. Department of Laboratory Medicine, Medical Microbiology, Ghent University Hospital, Ghent, Belgium

6. Department of Laboratory Medicine, Ghent University Hospital, Ghent, Belgium

7. Department of Clinical Microbiology and Center for Interdisciplinary Research on Medicines, University Hospital of Liège, Liège, Belgium

8. Department of Clinical Chemistry, University Hospital of Liège, Liège, Belgium

9. Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium

10. Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium

Abstract

We evaluated the quantitative DiaSorin Liaison severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen test in symptomatic and asymptomatic individuals consulting their general practitioners (GPs) during a period of stable intense virus circulation (213/100,000 habitants per day). Leftover reverse transcription-PCR (RT-PCR) positive ( n = 204) and negative ( n = 210) nasopharyngeal samples were randomly selected among fresh routine samples collected from patients consulting their GPs.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00374-21

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