Convenience of Serum for Visceral Leishmaniasis Diagnosis by PCR

Author:

Fissore Cristel1,Delaunay Pascal1,Ferrua Bernard1,Rosenthal Eric1,Del Giudice Pascal1,Aufeuvre Jean-Pierre2,Le Fichoux Yves1,Marty Pierre1

Affiliation:

1. Equipe de Recherche sur les Leishmanioses, Faculté de Médecine, Université de Nice—Sophia-Antipolis and Laboratoire de Parasitologie-Mycologie, Centre Hospitalier Universitaire de Nice, Nice, France

2. Centre de Transfusion Sanguine, Monaco

Abstract

ABSTRACT In this retrospective study, the usefulness of a PCR performed on serum for primary diagnosis and monitoring of Mediterranean visceral leishmaniasis (MVL) was assessed. In the case of primary diagnosis of MVL, the serum PCR showed a sensitivity of 97% and a specificity of 95%, with positive and negative predictive values of 94 and 97%, respectively.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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