METABOLIC ACTIVITY IN COXIELLA BURNETII

Abstract

Ormsbee, Richard A. (Rocky Mountain Laboratory, Hamilton, Mont.), and Marius G. Peacock . Metabolic activity in Coxiella burnetii . J. Bacteriol. 88: 1205–1210. 1964.—Purified suspensions of Coxiella burnetii were shown to utilize α-ketoglutarate, succinate, fumarate, malate, oxaloacetate, pyruvate, glutamate, and serine. The addition of nicotinamide adenine dinucleotide + was necessary to elicit the maximal rate of oxygen uptake with l -glutamate as substrate, but was unnecessary when other substrates were employed. It was concluded that the Krebs cycle of intermediary carbohydrate metabolism probably operates within C. burnetii , and that pyruvate is the chief energy source.