A Conserved Gene Cluster Rules Anaerobic Oxidative Degradation of l -Ornithine-Reference-Cited by-同舟云学术

A Conserved Gene Cluster Rules Anaerobic Oxidative Degradation of l -Ornithine

Published:2009-05 Issue:9 Volume:191 Page:3162-3167
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Fonknechten Nuria¹²³,Perret Alain¹²³,Perchat Nadia¹²³,Tricot Sabine¹²³,Lechaplais Christophe¹²³,Vallenet David¹²³,Vergne Carine¹²³,Zaparucha Anne¹²³,Le Paslier Denis¹²³,Weissenbach Jean¹²³,Salanoubat Marcel¹²³

Affiliation:

1. CEA, DSV, IG, Genoscope, 2 rue Gaston Crémieux, Evry F-91057, France

2. CNRS-UMR 8030, Evry F-91057, France

3. UEVE, Université d'Evry, Evry F-91057, France

Abstract

ABSTRACT For the ornithine fermentation pathway, described more than 70 years ago, genetic and biochemical information are still incomplete. We present here the experimental identification of the last four missing genes of this metabolic pathway. They encode l -ornithine racemase, (2 R ,4 S )-2,4-diaminopentanoate dehydrogenase, and the two subunits of 2-amino-4-ketopentanoate thiolase. While described only for the Clostridiaceae to date, this pathway is shown to be more widespread.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.01777-08

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