Emerging Mechanisms of G 1 /S Cell Cycle Control by Human and Mouse Cytomegaloviruses

Author:

Bogdanow Boris1,Phan Quang Vinh2,Wiebusch Lüder2ORCID

Affiliation:

1. Department of Structural Biology, Leibniz-Forschungsinstitut für Molekulare Pharmakologie, Berlin, Germany

2. Department of Pediatrics, Division of Oncology and Hematology, Charité - Universitätsmedizin Berlin, Berlin, Germany

Abstract

Cytomegaloviruses (CMVs) are among the largest pathogenic viruses in mammals. To enable replication of their long double-stranded DNA genomes, CMVs induce profound changes in cell cycle regulation.

Funder

Deutsche Forschungsgemeinschaft

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Reference148 articles.

1. Virchow R. 1858. Die Cellularpathologie in ihrer Begründung auf physiologische und pathologische Gewebelehre. Verlag von August Hirschwald, Berlin, Germany.

2. Morgan DO. 2007. The cell cycle: principles of control. New Science Press, London, United Kingdom.

3. Cell cycle proteins as promising targets in cancer therapy

4. The broken cycle: E2F dysfunction in cancer

5. Breaking Bad: How Viruses Subvert the Cell Cycle

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