The CIAMIB: a Large and Metabolically Diverse Collection of Inflammation-Associated Bacteria from the Murine Gut

Author:

Wong Erin Oi-Yan1,Brownlie Emma Joan Elizabeth1,Ng Katharine Michelle23,Kathirgamanathan Sornnujah1,Yu Feiqiao Brian4ORCID,Merrill Bryan D.5ORCID,Huang Kerwyn Casey456ORCID,Martin Alberto7,Tropini Carolina238ORCID,Navarre William Wiley1ORCID

Affiliation:

1. Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

2. School of Biomedical Engineering, University of British Columbia, Vancouver, Canada

3. Department of Microbiology and Immunology, University of British Columbia, Vancouver, Canada

4. Chan Zuckerberg Biohub, San Francisco, California, USA

5. Department of Microbiology and Immunology, Stanford University of School of Medicine, Stanford, California, USA

6. Department of Bioengineering, Stanford University, Stanford, California, USA

7. Department of Immunology, University of Toronto, Toronto, Ontario, Canada

8. Humans and the Microbiome Program, Canadian Institute for Advanced Research, Toronto, Canada

Abstract

Attempts to explore the role of the microbiota in animal physiology have resulted in large-scale efforts to cultivate the thousands of microbes that are associated with humans. In contrast, relatively few lab mouse-associated bacteria have been isolated, despite the fact that the overwhelming number of studies on the microbiota use laboratory mice that are colonized with microbes that are quite distinct from those in humans.

Funder

HHS | National Institutes of Health

W. Garfield Weston Foundation

Gouvernement du Canada | Canadian Institutes of Health Research

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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