Multiple Regulatory Mechanisms Control the Production of CmrRST, an Atypical Signal Transduction System in Clostridioides difficile-Reference-Cited by-同舟云学术

Multiple Regulatory Mechanisms Control the Production of CmrRST, an Atypical Signal Transduction System in Clostridioides difficile

Published:2022-02-22 Issue:1 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Garrett Elizabeth M.¹,Mehra Anchal¹,Sekulovic Ognjen²,Tamayo Rita¹^ORCID

Affiliation:

1. Department of Microbiology and Immunology, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, USA

2. Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USA

Abstract

Clostridioides difficile is a leading cause of hospital-acquired intestinal infections in the United States. The CmrRST signal transduction system controls numerous physiological traits and processes in C. difficile , including cell and colony morphology, motility, biofilm formation, and virulence.

Funder

Gouvernement du Canada | Canadian Institutes of Health Research

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.02969-21

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