Author:
Potron Anaïs,Poirel Laurent,Nordmann Patrice
Abstract
ABSTRACTPlasmid-mediated carbapenem-hydrolyzing β-lactamases are becoming emerging threats withEnterobacteriaceae. In particular, the carbapenem-hydrolyzing class D β-lactamase OXA-48 and its derivative OXA-181 have been reported increasingly worldwide. Using a PCR-based strategy, environmental samples were screened forblaOXA-48-like genes.Shewanella xiamenensis, an environmental species from marine and freshwater, was identified as the progenitor of theblaOXA-181gene. This work identifies the reservoir of an emerging carbapenemase gene that is clinically significant.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
91 articles.
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