Novel Plasmid Carrying Mobile Colistin Resistance Gene mcr-4.3 and Mercury Resistance Genes in Shewanella baltica: Insights into Mobilization of mcr-4.3 in Shewanella Species-Reference-Cited by-同舟云学术

Novel Plasmid Carrying Mobile Colistin Resistance Gene mcr-4.3 and Mercury Resistance Genes in Shewanella baltica: Insights into Mobilization of mcr-4.3 in Shewanella Species

Published:2022-12-21 Issue:6 Volume:10 Page:
ISSN:2165-0497
Container-title:Microbiology Spectrum
language:en
Short-container-title:Microbiol Spectr

Author:

Marathe Nachiket P.¹^ORCID,Salvà-Serra Francisco²³⁴⁵^ORCID,Nimje Priyank S.¹^ORCID,Moore Edward R. B.²³⁴^ORCID

Affiliation:

1. Institute of Marine Research, Bergen, Norway

2. Department of Infectious Diseases, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

3. Department of Clinical Microbiology, Culture Collection University of Gothenburg (CCUG), Sahlgrenska University Hospital, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

4. Centre for Antibiotic Resistance Research (CARe), University of Gothenburg, Gothenburg, Sweden

5. Microbiology, Department of Biology, University of the Balearic Islands, Palma de Mallorca, Spain

Abstract

We identified two new plasmids in Shewanella baltica isolated from wild Atlantic mackerel ( Scomber scombrus ) collected from the northern North Sea, one plasmid carrying the mcr-4.3 gene for colistin resistance and the operon merRPAT for mercury resistance and the other carrying multiple heavy metal resistance genes. The marine environment has been recognized as a source of new resistance genes that are found in human pathogens.

Funder

Havforskningsinstituttet

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Cell Biology,Microbiology (medical),Genetics,General Immunology and Microbiology,Ecology,Physiology

Link

https://journals.asm.org/doi/pdf/10.1128/spectrum.02037-22

Reference24 articles.

1. The Epidemiology of Carbapenem-Resistant Enterobacteriaceae: The Impact and Evolution of a Global Menace

2. Colistin: the re-emerging antibiotic for multidrug-resistant Gram-negative bacterial infections

3. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study