Affiliation:
1. Department of Biochemistry, University of Connecticut Health Center, Farmington 06030.
Abstract
The zymogen of the protease (GPR) that initiates protein degradation during spore germination in Bacillus species is not activated in vitro under normal physiological conditions. However, there is rapid, acid-pH-dependent, zero-order, proteolytic activation of the purified zymogen in high concentrations of dimethyl sulfoxide. These findings provide further evidence that GPR activates itself during sporulation.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
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