Affiliation:
1. Department of Chemical Engineering, Pennsylvania State University, University Park, Pennsylvania
Abstract
ABSTRACT
Anaerobic glucose oxidation was coupled to xylose reduction in a nonfermentative
Escherichia coli
strain expressing NADPH-dependent xylose reductase. Xylitol production serves as the primary means of NAD(P)
+
regeneration, as glucose is converted primarily to acetate and CO
2
. The membrane-bound transhydrogenase PntAB is required to achieve the maximum theoretical yield of four moles of xylitol per mole of glucose consumed.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Cited by
20 articles.
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