In Vivo-Induced Genes in Pseudomonas aeruginosa-Reference-Cited by-同舟云学术

In Vivo-Induced Genes in Pseudomonas aeruginosa

Published:2000-04 Issue:4 Volume:68 Page:2359-2362
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Handfield Martin¹,Lehoux Dario E.¹,Sanschagrin François¹,Mahan Michael J.²,Woods Donald E.³,Levesque Roger C.¹

Affiliation:

1. Microbiologie Moléculaire et Génie des Protéines, Pavillon Charles-Eugène Marchand, Faculté de Médecine, Université Laval, Sainte-Foy, Québec, Canada G1K 7P41;

2. Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, California 931062

3. Department of Microbiology and Infectious Diseases, University of Calgary, Alberta, Canada T2N 4M13; and

Abstract

ABSTRACT In vivo expression technology was used for testing Pseudomonas aeruginosa in the rat lung model of chronic infection and in a mouse model of systemic infection. Three of the eight ivi proteins found showed sequence identity to known virulence factors involved in iron acquisition via an open reading frame (called pvdI ) implicated in pyoverdine biosynthesis, membrane biogenesis (FtsY), and adhesion (Hag2).

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.68.4.2359-2362.2000

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