vhp Is a Fibrinogen-Binding Protein Related to vWbp in Staphylococcus aureus

Author:

Thomas Sheila1,Arora Srishtee1,Liu Wen1,Churion Kelly1,Wu You1,Höök Magnus1

Affiliation:

1. Center for Infectious and Inflammatory Diseases, Institute of Biosciences and Technology, Texas A&M University Health Science Center, Houston, Texas, USA

Abstract

The life-threatening diseases caused by multidrug-resistant Staphylococcus aureus strains are a worldwide medical problem due to treatment limitations and the lack of an effective vaccine. The ability of S. aureus to coat itself with a protective fibrinogen (Fg)/fibrin shield allows the organism to survive in blood and to disseminate and cause invasive diseases.

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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