Culex tarsalis Is a Competent Host of the Insect-Specific Alphavirus Eilat Virus (EILV)

Author:

Joseph Renuka E.123,Urakova Nadya1,Werling Kristine L.123,Metz Hillery C.1,Montanari Kaylee1,Rasgon Jason L.123ORCID

Affiliation:

1. Department of Entomology, Pennsylvania State University, University Park, Pennsylvania, USA

2. Center for Infectious Disease Dynamics, Pennsylvania State University, University Park, Pennsylvania, USA

3. The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania, USA

Abstract

The recent discovery of insect-specific alphaviruses presents opportunities both to study the biology of virus host range and to develop them into tools against pathogenic arboviruses. Here, we characterize the host range and transmission of Eilat virus in five mosquito species.

Funder

Dorothy Foehr Huck and J. Lloyd Huck Endowment

HHS | National Institutes of Health

National Science Foundation

U.S. Department of Agriculture

Pennsylvania Department of Health

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference49 articles.

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2. Murray PR, Rosenthal KS, Pfaller MA. 2021. Togaviruses and flaviviruses, 515–526. In Medical microbiology. Elsevier, Amsterdam, Netherlands.

3. Eilat virus, a unique alphavirus with host range restricted to insects by RNA replication

4. Agua Salud alphavirus defines a novel lineage of insect-specific alphaviruses discovered in the New World

5. Discovery of a novel alphavirus related to Eilat virus

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