The Interaction between the Ribosomal Stalk Proteins and Translation Initiation Factor 5B Promotes Translation Initiation-Reference-Cited by-同舟云学术

The Interaction between the Ribosomal Stalk Proteins and Translation Initiation Factor 5B Promotes Translation Initiation

Published:2018-08-15 Issue:16 Volume:38 Page:
ISSN:0270-7306
Container-title:Molecular and Cellular Biology
language:en
Short-container-title:Mol Cell Biol

Author:

Murakami Ryo¹²,Singh Chingakham Ranjit²,Morris Jacob²,Tang Leiming²,Harmon Ian²,Takasu Azuma²,Miyoshi Tomohiro¹,Ito Kosuke¹,Asano Katsura²,Uchiumi Toshio¹

Affiliation:

1. Department of Biology, Faculty of Science, Niigata University, Niigata, Japan

2. Molecular, Cellular, and Developmental Biology Program, Division of Biology, Kansas State University, Manhattan, Kansas, USA

Abstract

Ribosomal stalk proteins recruit translation elongation GTPases to the factor-binding center of the ribosome. Initiation factor 5B (eIF5B in eukaryotes and aIF5B in archaea) is a universally conserved GTPase that promotes the joining of the large and small ribosomal subunits during translation initiation.

Funder

HHS | NIH | National Institute of General Medical Sciences

Ministry of Education, Culture, Sports, Science and Technology

MEXT | Japan Society for the Promotion of Science

Publisher

American Society for Microbiology

Subject

Cell Biology,Molecular Biology

Link

https://journals.asm.org/doi/pdf/10.1128/MCB.00067-18

Reference63 articles.

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2. Translational Control

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4. Translation factor control of ribosome conformation during start codon selection

5. Real-time assembly landscape of bacterial 30S translation initiation complex

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