Piperaquine Pharmacokinetics during Intermittent Preventive Treatment for Malaria in Pregnancy-Reference-Cited by-同舟云学术

Piperaquine Pharmacokinetics during Intermittent Preventive Treatment for Malaria in Pregnancy

Published:2021-02-17 Issue:3 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Chotsiri Palang¹^ORCID,Gutman Julie R.²,Ahmed Rukhsana³⁴,Poespoprodjo Jeanne Rini⁵⁶⁷,Syafruddin Din⁴,Khairallah Carole³,Asih Puji B. S.⁴,L’lanziva Anne⁸,Otieno Kephas⁹,Kariuki Simon⁹^ORCID,Ouma Peter⁹,Were Vincent⁹,Katana Abraham¹⁰,Price Ric N.¹¹¹¹²,Desai Meghna²,ter Kuile Feiko O.³,Tarning Joel¹¹²^ORCID

Affiliation:

1. Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

2. Malaria Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

3. Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom

4. Malaria and Vector Resistance Laboratory, Eijkman Institute for Molecular Biology, Jakarta, Indonesia

5. Mimika District Health Authority, Timika, Papua, Indonesia

6. Timika Malaria Research Programme, Papuan Health and Community Development Foundation, Timika, Papua, Indonesia

7. Centre for Child Health and Department of Child Health, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia

8. Centers for Diseases Control and Prevention, Kisumu, Kenya

9. Kenya Medical Research Institute, Centre for Global Health Research, Kisumu, Kenya

10. Centers for Diseases Control and Prevention, Nairobi, Kenya

11. Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia

12. Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

Abstract

Dihydroartemisinin-piperaquine (DP) is a long-acting artemisinin combination treatment that provides effective chemoprevention and has been proposed as an alternative antimalarial drug for intermittent preventive therapy in pregnancy (IPTp). Several pharmacokinetic studies have shown that dose adjustment may not be needed for the treatment of malaria in pregnancy with DP.

Funder

Bill and Melinda Gates Foundation

Wellcome

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01150-20

Reference47 articles.

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2. Randomized, Double-Blind, Placebo-Controlled Trial of Monthly versus Bimonthly Dihydroartemisinin-Piperaquine Chemoprevention in Adults at High Risk of Malaria