Draft Genome Sequences and Genome Characterization of Three Toxigenic and Two Nontoxigenic Clostridioides difficile Clinical Isolates from Florida, USA

Author:

Wickramage Ishani1ORCID,Heuler Joshua1,Peng Zhong1,Alrabaa Sally2,Sun Xingmin1ORCID

Affiliation:

1. Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA

2. Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA

Abstract

Draft genome sequences of five Clostridioides difficile clinical isolates were obtained in Florida, USA. Three isolates, designated TGH29 (sequence type 1 [ST1]/clade 2), TGH79 (ST11/clade 5), and TGH91 (ST35/clade 1), contained toxin-encoding genes. The two nontoxigenic strains were classified as TGH114 (ST109/clade 4) and TGH132 (ST15/clade 1). Antimicrobial resistance determinants and plasmids were detected and putative prophages predicted in some isolates.

Funder

National Institutes of Health

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Genetics,Immunology and Microbiology (miscellaneous),Molecular Biology

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