NG-Test Carba 5 for Rapid Detection of Carbapenemase-Producing Enterobacterales from Positive Blood Cultures-Reference-Cited by-同舟云学术

NG-Test Carba 5 for Rapid Detection of Carbapenemase-Producing Enterobacterales from Positive Blood Cultures

Published:2019-05 Issue:5 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Takissian Julie¹²,Bonnin Rémy A.¹²³,Naas Thierry¹²³⁴^ORCID,Dortet Laurent¹²³⁴^ORCID

Affiliation:

1. EA7361 Structure, dynamic, function and expression of broad spectrum β-lactamases, Université Paris Sud, Université Paris Saclay, LabEx LERMIT, Faculty of Medicine, Le Kremlin-Bicêtre, France

2. Evolution and Ecology of Resistance to Antibiotics Unit, Institut Pasteur–APHP–Université Paris Sud, Paris, France

3. Associated French National Reference Center for Antibiotic Resistance: Carbapenemase-producing Enterobacteriaceae, Le Kremlin-Bicêtre, France

4. Bacteriology-Hygiene Unit, Assistance Publique/Hôpitaux de Paris, Bicêtre Hospital, Le Kremlin-Bicêtre, France

Abstract

The immunochromatographic assay, NG-test Carba 5 (NG Biotech), has been evaluated for detection of carbapenemase-producing Enterobacterales (CPE) from spiked blood cultures ( n = 205). It detected and discriminated in less than 30 minutes KPC, IMP, VIM, NDM, and OXA-48-like producers with a sensitivity and specificity of 97.7% and 96.1%, respectively.

Funder

Agence Nationale de la Recherche

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00011-19

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