Exploring Cluster-Dependent Antibacterial Activities and Resistance Pathways of NOSO-502 and Colistin against Enterobacter cloacae Complex Species

Author:

Pantel Lucile1,Guérin François23,Serri Marine1,Gravey François45ORCID,Houard Jessica1,Maurent Kelly1,Attwood Marie6,Noel Alan6,MacGowan Alasdair6,Racine Emilie1,Cattoir Vincent23ORCID,Gualtieri Maxime1ORCID

Affiliation:

1. Nosopharm, Nîmes, France

2. CHU de Rennes, Service de Bactériologie-Hygiène Hospitalière, Rennes, France

3. Université de Rennes 1, Unité INSERM U1230 BRM, Rennes, France

4. Université de Caen Normandie, Dynamicure, INSERM U1311, CHU de Caen, Caen, France

5. CHU de Caen, service de bactériologie, Caen, France

6. Bristol Centre for Antimicrobial Research and Evaluation (BCARE), Infection Sciences, Southmead Hospital, Bristol, United Kingdom

Abstract

The Enterobacter cloacae complex (ECC) is a group of diverse environmental and clinically relevant bacterial species associated with a variety of infections in humans. ECC have emerged as one of the leading causes of nosocomial infections worldwide.

Funder

Innovative Medicines Initiative

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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