Affiliation:
1. Department of Oral Biology, College of Dentistry, University of Nebraska Medical Center, Lincoln, Nebraska 68583-0740
Abstract
An extracellular polysaccharide was purified from culture supernatants of
Capnocytophaga ochracea
25, a gram-negative bacillus associated with human periodontal disease. The extracellular polysaccharide suppressed in vitro mitogenic responses of murine splenic lymphocytes to concanavalin A and lipopolysaccharide. This suppression wad dose dependent, persisted up to 120 h, and was not caused by direct toxicity of the extracellular polysaccharide.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference18 articles.
1. Regulation of immunoglobulin synthesis by dextran;Battisto J.;J. Exp. Med.,1973
2. Modulation of murine Iymphocyte mitogen responses by glycerol-teichoic acid;Bolton R. W.;Immunol. Commun.,1981
3. Colonization of the cementum surface of teeth by oral gram-negative bacteria;Celesk R. A.;Infect. Immun.,1979
4. The modulating effect of cholera enterotoxin on the immune response;Chisari F. V.;J. Immunol.,1974
5. The primary immune response in mice. I. The enhancement and suppression of hemolysin production by bacterial endotoxin;Franzl R. W.;J. Exp. Med.,1968
Cited by
24 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献