Evaluation of LDBio Aspergillus ICT Lateral Flow Assay for IgG and IgM Antibody Detection in Chronic Pulmonary Aspergillosis

Author:

Stucky Hunter Elizabeth1ORCID,Richardson Malcolm D.12,Denning David W.13

Affiliation:

1. Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom

2. Mycology Reference Centre Manchester, Manchester University NHS Foundation Trust, Manchester, United Kingdom

3. National Aspergillosis Centre, Manchester University NHS Foundation Trust, Manchester, United Kingdom

Abstract

Detecting Aspergillus -specific IgG is critical to diagnosing chronic pulmonary aspergillosis (CPA). Existing assays are often cost- and resource-intensive and not compatible with resource-constrained laboratory settings. LDBio Diagnostics has recently commercialized a lateral flow assay based on immunochromatographic technology (ICT) that detects Aspergillus antibodies (IgG and IgM) in less than 30 min, requiring minimal laboratory equipment.

Funder

Newton Fund

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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