Affiliation:
1. Servicio de Micologia, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain
Abstract
ABSTRACT
A phylogenetic analysis was performed for 34
Aspergillus
strains belonging to section
Nigri
. Molecular methods allowed for the correct classification into three different clades (
A. niger
,
A. tubingensis
, and
A. foetidus
). Correlation with in vitro itraconazole susceptibility distinguished the following three profiles: susceptible, resistant, and showing a paradoxical effect. A number of different species whose morphological features resemble those of
A. niger
showed unusual MICs to itraconazole that have never been described for the
Aspergillus
genus.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
70 articles.
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