Effective Treatment of Staphylococcal Enterotoxin B Aerosol Intoxication in Rhesus Macaques by Using Two Parenterally Administered High-Affinity Monoclonal Antibodies-Reference-Cited by-同舟云学术

Effective Treatment of Staphylococcal Enterotoxin B Aerosol Intoxication in Rhesus Macaques by Using Two Parenterally Administered High-Affinity Monoclonal Antibodies

Published:2019-05 Issue:5 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Verreault Daniel¹²³,Ennis Jane⁴,Whaley Kevin⁴,Killeen Stephanie Z.¹²³,Karauzum Hatice⁵,Aman M. Javad⁵,Holtsberg Rick⁵,Doyle-Meyers Lara¹²³,Didier Peter J.¹²³,Zeitlin Larry⁴,Roy Chad J.¹²³⁶

Affiliation:

1. Division of Microbiology, Tulane National Primate Research Center, Covington, Louisiana, USA

2. Division of Veterinary Medicine, Tulane National Primate Research Center, Covington, Louisiana, USA

3. Division of Comparative Pathology, Tulane National Primate Research Center, Covington, Louisiana, USA

4. Mapp Biopharmaceutical, San Diego, California, USA

5. Integrated BioTherapeutics, Inc., Gaithersburg, Maryland, USA

6. Department of Microbiology and Immunology, Tulane School of Medicine, New Orleans, Louisiana, USA

Abstract

Staphylococcal enterotoxin B (SEB) is a protein exotoxin found on the cell surface of Staphylococcus aureus that is the source for multiple pathologies in humans. When purified and concentrated in aerosol form, SEB can cause an acute and often fatal intoxication and thus is considered a biological threat agent.

Funder

HHS | National Institutes of Health

HHS | NIH | NIH Office of the Director

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02049-18

Reference40 articles.

1. Ulrich RG. 2007. Staphylococcal enterotoxin B and related toxins. Borden Insitute, Washington, DC.

2. Toxicity of staphylococcal enterotoxins potentiated by lipopolysaccharide: major histocompatibility complex class II molecule dependency and cytokine release

3. Staphylococcal enterotoxin-mediated human T-T cell interactions;Koning F;J Immunol,1992

4. Superantigens: Biology, immunology, and potential role in disease

5. Cross-linking of MHC class II molecules by staphylococcal enterotoxin A is essential for antigen-presenting cell and T cell activation;Tiedemann RE;J Immunol,1996

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Humanized mouse model for vaccine evaluation: an overview;Clinical and Experimental Vaccine Research;2024

2. Bio warfare and terrorism: Toxins and other mid-spectrum agents;Encyclopedia of Toxicology;2024

3. Staphylococcal Enterotoxin B Attack;Ciottone's Disaster Medicine;2024

4. The Immunotherapy Strategies of Staphylococcus aureus Enterotoxin Poisoning;PROG BIOCHEM BIOPHYS;2023

5. Lateral Flow Strip Biosensors for Foodborne Pathogenic Bacteria via Direct and Indirect Sensing Strategies: A Review;Journal of Agricultural and Food Chemistry;2023-06-30