Affiliation:
1. Department of Pharmacy, University of Sydney, Sydney, N.S.W. 2006, Australia
Abstract
The activities are reported of sodium salts of several
n
-alkylsalicylic acids against
Staphylococcus aureus, Pseudomonas aeruginosa, Mycobacterium phlei
, and
Candida albicans
. The acids had alkyl substituents of 1 to 18 carbon atoms in the 3, 4, or 5 positions relative to the carboxyl group of salicylic acid. Generally, the antimicrobial properties were typical of anionic surface-active agents although the salicylates are more potent than most of these, particularly against
S. aureus
.
Publisher
American Society for Microbiology
Subject
General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
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