Insights into the Antibacterial Mechanism of Action of Chelating Agents by Selective Deprivation of Iron, Manganese, and Zinc-Reference-Cited by-同舟云学术

Insights into the Antibacterial Mechanism of Action of Chelating Agents by Selective Deprivation of Iron, Manganese, and Zinc

Published:2022-01-25 Issue:2 Volume:88 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Paterson Joy R.¹,Beecroft Marikka S.¹,Mulla Raminder S.²,Osman Deenah¹,Reeder Nancy L.³,Caserta Justin A.³,Young Tessa R.¹,Pettigrew Charles A.³,Davies Gareth E.⁴,Williams J. A. Gareth²,Sharples Gary J.¹^ORCID

Affiliation:

1. Department of Biosciences, Durham University, Durham, United Kingdom

2. Department of Chemistry, Durham University, Durham, United Kingdom

3. Procter and Gamble, Mason Business Center, Cincinnati, Ohio, USA

4. Procter and Gamble Technical Centres Ltd., Reading, Berkshire, United Kingdom

Abstract

Chelating agents are widely used in industry and consumer goods to control metal availability, with bacterial growth restriction as a secondary benefit for preservation. However, the antibacterial mechanism of action of chelants is largely unknown, particularly with respect to the impact on cellular metal concentrations.

Funder

Procter and Gamble

Royal Commission for the Exhibition of 1851

UKRI | Biotechnology and Biological Sciences Research Council

UKRI | Engineering and Physical Sciences Research Council

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.01641-21

Reference88 articles.