Ivermectin Impairs the Development of Sexual and Asexual Stages of Plasmodium falciparum In Vitro-Reference-Cited by-同舟云学术

Ivermectin Impairs the Development of Sexual and Asexual Stages of Plasmodium falciparum In Vitro

Published:2019-08 Issue:8 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

de Carvalho Lais Pessanha¹²³,Sandri Thaisa Lucas¹²⁴,José Tenório de Melo Edésio³,Fendel Rolf¹²⁵,Kremsner Peter G.¹²⁵,Mordmüller Benjamin¹²⁵,Held Jana¹²⁵

Affiliation:

1. Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany

2. German Centre for Infection Research, Tübingen, Germany

3. Laboratory of Cell and Tissue Biology, Center for Biosciences and Biotechnology, State University of North Fluminense Darcy Ribeiro, Rio de Janeiro, Brazil

4. Laboratory of Molecular Immunopathology, Clinical Hospital, Federal University of Paraná, Curitiba, Brazil

5. Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon

Abstract

Ivermectin is the drug of choice for many parasitic infections, with more than one billion doses being distributed in onchocerciasis programs. The drug has been put into focus recently by the malaria community because of its potential to kill blood-sucking mosquitoes, thereby reducing malaria transmission.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00085-19

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