Characterization of Hemolytic Escherichia coli Strains in Ferrets: Recognition of Candidate Virulence Factor CNF1-Reference-Cited by-同舟云学术

Characterization of Hemolytic Escherichia coli Strains in Ferrets: Recognition of Candidate Virulence Factor CNF1

Published:2004-12 Issue:12 Volume:42 Page:5904-5908
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Marini Robert P.¹,Taylor Nancy S.¹,Liang Alvin Y.²,Knox Kimberly A.¹²,Peña Jeremy Andrew³,Schauer David B.¹²,Fox James G.¹²

Affiliation:

1. Division of Comparative Medicine

2. Biological Engineering Division, Massachusetts Institute of Technology, Cambridge, Massachusetts

3. Department of Pathology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas

Abstract

ABSTRACT Diseases associated with Escherichia coli infection are the subject of renewed interest due to emerging conditions such as hemolytic uremia syndrome. A collection of 15 strains of beta-hemolytic E. coli was isolated from diarrheic feces and diseased tissues of ferrets. All 15 strains were positive in specific PCR assays for the presence of hlyA , pap1 , and cnf1 . Seven of the cnf1 -positive isolates were tested and shown to have a cytopathic effect on HeLa cell monolayers. The pathogenesis of these strains warrants future study.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.42.12.5904-5908.2004

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