Neutralizing Antibody Response in Bovine Serum and Nasal and Salivary Secretions After Immunization with Live or Inactivated Foot-and-Mouth Disease Virus

Author:

Figueroa Felipe1,Ohlbaum Adela1,Contreras Guillermo1

Affiliation:

1. Unidad de Virología, Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad de Chile, Santiago, Chile

Abstract

Calves develop nasal and salivary neutralizing antibodies against foot-and-mouth disease virus after nasal inoculation with live virus. Nasal and salivary antibody was not detected after exposure to inactive virus. Serum antibodies were induced by live and inactive virus given subcutaneously. Passively acquired antibodies were detected as long as 7 months after birth.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference11 articles.

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2. The half-life of homologous gamma globulin (antibody) in several species;Dixon F. J.;J. Exp. Med.,1952

3. Chemical inactivation oft'oot-andmouth disease virus;Fellowes 0.;Ann. N. Y. Acad. Sci.,1960

4. Transter of neutralizing antibody by colostrum to calves bortn ot ftoot-and-mouth disease vaccinated dams. ,J;Graves J. H.;Immunol.,1963

5. Hoskins J. M. 1967. Virological procedures p. 187-191 237-240 257-260. Butterworths London.

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