Identification and Characterization of Defective Viral Genomes in Ebola Virus-Infected Rhesus Macaques-Reference-Cited by-同舟云学术

Identification and Characterization of Defective Viral Genomes in Ebola Virus-Infected Rhesus Macaques

Published:2021-08-10 Issue:17 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Johnson Rebecca I.¹,Boczkowska Beata²,Alfson Kendra²,Weary Taylor²,Menzie Heather²,Delgado Jenny²,Rodriguez Gloria²,Carrion Ricardo²,Griffiths Anthony¹²^ORCID

Affiliation:

1. Boston University School of Medicine, Department of Microbiology, National Emerging Infectious Diseases Laboratory, Boston, Massachusetts, USA

2. Disease Intervention and Prevention, Texas Biomedical Research Institute, San Antonio, Texas, USA

Abstract

The study of filovirus pathogenesis is critical for understanding the consequences of infection and for the development of strategies to ameliorate future outbreaks. Defective viral genomes (DVGs) have been detected during EBOV infections in vitro ; however, their presence in in vivo infections remains unknown.

Funder

HHS | Biomedical Advanced Research and Development Authority

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00714-21

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