Response Regulator CD1688 Is a Negative Modulator of Sporulation in Clostridioides difficile-Reference-Cited by-同舟云学术

Response Regulator CD1688 Is a Negative Modulator of Sporulation in Clostridioides difficile

Published:2022-08-16 Issue:8 Volume:204 Page:
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Kempher Megan L.¹²^ORCID,Morris Savannah C.¹,Shadid Tyler M.²,Menon Smita K.¹,Ballard Jimmy D.²^ORCID,West Ann H.¹

Affiliation:

1. University of Oklahoma, Department of Chemistry and Biochemistry, Norman, Oklahoma, USA

2. University of Oklahoma Health Sciences Center, Department of Microbiology and Immunology, Oklahoma City, Oklahoma, USA

Abstract

Clostridioides difficile causes severe gastrointestinal illness and is a leading cause of nosocomial infections in the United States. This pathogen produces metabolically dormant spores that are the major vehicle of transmission between hosts.

Funder

Oklahoma Center for the Advancement of Science and Technology

Grayce B. Kerr Endowment

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of General Medical Sciences

Price Family Foundation

Research Corporation for Scientific Advancement

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.00130-22

Reference63 articles.

1. Identification of Clostridium difficile as a cause of pseudomembranous colitis.

2. Clostridioides difficile Biology: Sporulation, Germination, and Corresponding Therapies for C. difficile Infection

3. Epidemiology of Recurrences or Reinfections of Clostridium difficile -Associated Diarrhea

4. Proteomic and Genomic Characterization of Highly Infectious Clostridium difficile 630 Spores

5. Hypervirulent Clostridium difficile PCR-Ribotypes Exhibit Resistance to Widely Used Disinfectants

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