Evaluation of the Cavidi ExaVir Load Assay (Version 3) for Plasma Human Immunodeficiency Virus Type 1 Load Monitoring-Reference-Cited by-同舟云学术

Evaluation of the Cavidi ExaVir Load Assay (Version 3) for Plasma Human Immunodeficiency Virus Type 1 Load Monitoring

Published:2009-09 Issue:9 Volume:47 Page:3011-3013
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Greengrass Vicki L.¹,Plate Megan M.¹,Steele Pauline M.¹,Denholm Justin T.²,Cherry Catherine L.¹²³,Morris Lisa M.¹,Hearps Anna¹,Crowe Suzanne M.¹²³

Affiliation:

1. Clinical Research Laboratory, Centre for Virology, Macfarlane Burnet Institute for Medical Research and Public Health, 85 Commercial Road, Melbourne, Australia

2. Infectious Diseases Unit, Alfred Hospital, Commercial Road, Melbourne, Australia

3. Department of Medicine, Monash University, 85 Commercial Road, Melbourne, Australia

Abstract

ABSTRACT We evaluated the new low-cost ExaVir Load (version 3) reverse transcriptase viral load assay against the Roche Cobas Amplicor assay. Results for samples tested using the reverse transcriptase assay correlated well with those obtained with the Roche assay ( r = 0.85; n = 202). The version 3 reverse transcriptase assay shows improved sensitivity compared to the previous version.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00805-09

Reference21 articles.

1. Braun, P., R. Ehret, F. Wiesmann, F. Zabbai, M. Knickmann, R. Kuhn, S. Thamm, G. Warnat, and H. Knechten. 2007. Comparison of four commercial quantitative HIV-1 assays for viral load monitoring in clinical daily routine. Clin. Chem. Lab. Med.45:93-99.

2. Crowe, S., S. Turnbull, R. Oelrichs, and A. Dunne. 2003. Monitoring of human immunodeficiency virus infection in resource-constrained countries. Clin. Infect. Dis.37:S25-S35.

3. DiDomenico, N., H. Link, R. Knobel, T. Caratsch, W. Weschler, Z. G. Loewy, and M. Rosenstraus. 1996. COBAS AMPLICOR: fully automated RNA and DNA amplification and detection system for routine diagnostic PCR. Clin. Chem.42:1915-1923.

4. Fiscus, S. A., S. M. Crowe, L. Demeter, C. Jennings, V. Miller, R. Respess, W. Stevens, and Forum for Collaborative HIV Research Alternative Viral Load Assay Working Group. 2006. HIV-1 viral load assays for resource-limited settings. PLoS Med.3:e417.

5. Greengrass, V., M. M. Plate, P. M. Steele, R. Taqi, L. van Rooijen, Y. Sun, L. M. Morris, and S. M. Crowe. 2007. HIV monitoring in laboratories in resource limited areas. J. Chin. Clin. Med.2:469-479.

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Diagnosis of Human Immunodeficiency Virus Infection;Clinical Microbiology Reviews;2018-12-19

2. Assessment of the Cavidi ExaVir Load Assay for Monitoring Plasma Viral Load in HIV-2-Infected Patients;Journal of Clinical Microbiology;2017-08

3. Impact of peer support on virologic failure in HIV-infected patients on antiretroviral therapy - a cluster randomized controlled trial in Vietnam;BMC Infectious Diseases;2016-12

4. Human Immunodeficiency Virus;Manual of Commercial Methods in Clinical Microbiology;2016-04-01

5. Can HIV reverse transcriptase activity assay be a low-cost alternative for viral load monitoring in resource-limited settings?;BMJ Open;2016-01