Detection and Analysis of Hepatitis C Virus Sequences in Cerebrospinal Fluid-Reference-Cited by-同舟云学术

Detection and Analysis of Hepatitis C Virus Sequences in Cerebrospinal Fluid

Published:2002-10 Issue:19 Volume:76 Page:10064-10068
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Laskus Tomasz¹,Radkowski Marek¹²,Bednarska Agnieszka³,Wilkinson Jeffrey¹,Adair Debra¹,Nowicki Marek⁴,Nikolopoulou Georgia B.⁴,Vargas Hugo¹,Rakela Jorge¹

Affiliation:

1. Division of Transplantation Medicine, Mayo Clinic, Scottsdale, Arizona 85259

2. Institute of Infectious Diseases, Medical Academy

3. Municipal Hospital for Infectious Diseases, Warsaw, Poland

4. Maternal-Child Virology Research Laboratory, University of Southern California, Los Angeles, California 90033

Abstract

ABSTRACT Hepatitis C virus (HCV) sequences were detected in cerebrospinal fluid (CSF) in 8 of 13 HCV-positive patients. In four patients harboring different virus strains in serum and peripheral blood mononuclear cells (PBMC), CSF-derived virus was similar to that found in PBMC, which suggests that PBMC could carry HCV into the brain.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.76.19.10064-10068.2002

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