Affiliation:
1. Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, Chengdu, People's Republic of China
Abstract
ABSTRACT
A novel 65.8-kb multidrug resistance transposon, designated Tn
6450
, was characterized in a
Proteus mirabilis
isolate from chicken in China. Tn
6450
contains 18 different antimicrobial resistance genes, including cephalosporinase gene
bla
DHA-1
and fluoroquinolone resistance genes
qnrA1
and
aac(6
′
)-Ib-cr
. It carries a class 1/2 hybrid integron composed of
intI2
and a 3′ conserved segment of the class 1 integron. Tn
6450
is derived from Tn
7
via acquisition of new mobile elements and resistance genes.
Funder
Scientific Research Foundation of Sichuan University
Special Fund for Agro-Scientific Research in the Public Interest of China
Earmarked Fund for Modern Agro-Industry Technology Research System
General Program of National Natural Science Foundation of China
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
20 articles.
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