Epidemiologic Distribution of the Arginine Catabolic Mobile Element among Selected Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Isolates

Author:

Goering Richard V.1,McDougal Linda K.2,Fosheim Greg E.2,Bonnstetter Kristin K.1,Wolter Daniel J.1,Tenover Fred C.2

Affiliation:

1. Creighton University School of Medicine, Omaha, Nebraska, 68178

2. Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30333

Abstract

ABSTRACT We tested 214 Staphylococcus aureus isolates for the arcA locus of the arginine catabolic mobile element (ACME). All USA300 SCC mec IVa isolates, but no isolates containing other SCC mec subtypes, were arcA positive. arcA was also detected in selected methicillin-susceptible USA300 and methicillin-resistant USA100 isolates. DNA sequence analysis confirmed the integration of ACME in orfX .

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference21 articles.

1. Centers for Disease Control and Prevention. 1999. Four pediatric deaths from community-acquired methicillin-resistant Staphylococcus aureus—Minnesota and North Dakota, 1997-1999. Morb. Mortal. Wkly. Rep.48:707-710.

2. Centers for Disease Control and Prevention. 2003. Methicillin-resistant Staphylococcus aureus infections in correctional facilities—Georgia, California, and Texas, 2001-2003. Morb. Mortal. Wkly. Rep.52:992-996.

3. Performance standards for antimicrobial susceptibility testing. 2006

4. Intercontinental Spread of a Multidrug-Resistant MethicillinResistant Staphylococcus aureus Clone

5. Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus

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