In Vitro Development of Resistance to Telithromycin (HMR 3647), Four Macrolides, Clindamycin, and Pristinamycin in Streptococcus pneumoniae-Reference-Cited by-同舟云学术

In Vitro Development of Resistance to Telithromycin (HMR 3647), Four Macrolides, Clindamycin, and Pristinamycin in Streptococcus pneumoniae

Published:2000-02 Issue:2 Volume:44 Page:414-417
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Davies Todd A.¹,Dewasse Bonifacio E.¹,Jacobs Michael R.²,Appelbaum Peter C.¹

Affiliation:

1. Department of Pathology (Clinical Microbiology), Hershey Medical Center, Hershey, Pennsylvania 17033,1 and

2. Department of Pathology (Clinical Microbiology), Case Western Reserve University, Cleveland, Ohio 441062

Abstract

ABSTRACT The ability of 50 sequential subcultures in subinhibitory concentrations of telithromycin (HMR 3647), azithromycin, clarithromycin, erythromycin A, roxithromycin, clindamycin, and pristinamycin to select for resistance was studied in five macrolide-susceptible and six macrolide-resistant pneumococci containing mefE or ermB . Telithromycin selected for resistance less often than the other drugs.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.44.2.414-417.2000

Reference9 articles.

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