Disseminated Geotrichum candidum infection

Author:

Kassamali H1,Anaissie E1,Ro J1,Rolston K1,Kantarjian H1,Fainstein V1,Bodey G P1

Affiliation:

1. Department of Internal Medicine, University of Texas M. D. Anderson Hospital and Tumor Institute, Houston 77030.

Abstract

The pathogenicity of the fungus Geotrichum candidum in humans has not been clearly defined. A patient with acute leukemia who developed a fatal disseminated G. candidum infection while neutropenic is described. At autopsy examination, this patient was misdiagnosed on the basis of histopathology as having disseminated candidiasis until G. candidum was isolated from postmortem culture specimens. The emergence of this organism as an occasional pathogen in leukemic patients is of interest and illustrates the importance of obtaining fungal cultures. There is a need for more effective drugs for antifungal prophylaxis and therapy.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference11 articles.

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3. Quantitative relationships between circulating leukocytes and infection in patients with acute leukemia. Ann. intern;Bodey G. P.;Med.,1966

4. Disseminated geotrichosis. Case report;Chang W. W. L.;Arch. Intern. Med.,1964

5. Bronchial geotrichosis with fungemia complicating bronchogenic carcinoma;Ghamande A. R.;Chest,1971

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