Validation and Application of an HPLC-DAD Method for Routine Therapeutic Drug Monitoring of Ceftobiprole-Reference-Cited by-同舟云学术

Validation and Application of an HPLC-DAD Method for Routine Therapeutic Drug Monitoring of Ceftobiprole

Published:2019-07 Issue:7 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Lima Benjamin¹,Bodeau Sandra¹²,Quinton Marie-Charlotte¹,Leven Cyril³,Lemaire-Hurtel Anne-Sophie¹,Bennis Youssef¹²

Affiliation:

1. Laboratory of Pharmacology and Toxicology, Department of Clinical Pharmacology, Amiens University Hospital, Amiens, France

2. MP3CV Laboratory, EA7517, University of Picardie Jules Verne, Amiens, France

3. Laboratory of Pharmacology and Toxicology, Brest University Hospital, Brest, France

Abstract

Ceftobiprole is a fifth-generation cephalosporin approved for the treatment of pneumonia, with a broad antibacterial spectrum, including potent activity against methicillin-resistant Staphylococcus aureus . As for the other cephalosporins, high pharmacokinetic variability and concentration-dependent neurotoxicity are expected.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.00515-19

Reference13 articles.

1. In vitro activity profile of ceftobiprole, an anti-MRSA cephalosporin, against recent Gram-positive and Gram-negative isolates of European origin

2. Ceftobiprole Activity against over 60,000 Clinical Bacterial Pathogens Isolated in Europe, Turkey, and Israel from 2005 to 2010

3. Pharmacokinetics and Dosing of Ceftobiprole Medocaril for the Treatment of Hospital- and Community-Acquired Pneumonia in Different Patient Populations

4. Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of β-lactams

5. Exposure to Ceftobiprole Is Associated with Microbiological Eradication and Clinical Cure in Patients with Nosocomial Pneumonia

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Ceftobiprole quantification in human serum by HPLC-UV to implement routine TDM in clinical practice;Clinica Chimica Acta;2024-07

2. New Antimicrobials for Gram-Positive Sustained Infections: A Comprehensive Guide for Clinicians;Pharmaceuticals;2023-09-15

3. Development and Validation of Highly Precise Methods for the Spectrophotometric Determination of Cefpirome in Pharmaceutical Dosage Forms;Indian Journal of Pharmaceutical Education and Research;2023-01-09

4. Study of Degradation Kinetics and Structural Analysis of Related Substances of Ceftobiprole by HPLC with UV and MS/MS Detection;International Journal of Molecular Sciences;2022-12-03

5. Optimizations of the Conditions for Ceftobiprole Determination in a Complex Matrix;Processes;2022-10-26