Fate of CMY-2-Encoding Plasmids Introduced into the Human Fecal Microbiota by Exogenous Escherichia coli-Reference-Cited by-同舟云学术

Fate of CMY-2-Encoding Plasmids Introduced into the Human Fecal Microbiota by Exogenous Escherichia coli

Published:2019-05 Issue:5 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Anjum Mehreen¹^ORCID,Madsen Jonas Stenløkke²,Nesme Joseph²^ORCID,Jana Bimal¹,Wiese Maria³,Jasinskytė Džiuginta¹,Nielsen Dennis Sandris³,Sørensen Søren Johannes²^ORCID,Dalsgaard Anders¹,Moodley Arshnee¹,Bortolaia Valeria⁴,Guardabassi Luca⁵

Affiliation:

1. Department of Veterinary and Animal Sciences, University of Copenhagen, Frederiksberg, Denmark

2. Department of Biology, University of Copenhagen, Copenhagen, Denmark

3. Department of Food Science, University of Copenhagen, Frederiksberg, Denmark

4. National Food Institute, Technical University of Denmark, Lyngby, Denmark

5. Department of Pathobiology and Population Sciences, The Royal Veterinary College, Hatfield, Hertfordshire, United Kingdom

Abstract

The gut is a hot spot for transfer of antibiotic resistance genes from ingested exogenous bacteria to the indigenous microbiota. The objective of this study was to determine the fate of two nearly identical bla CMY-2 -harboring plasmids introduced into the human fecal microbiota by two Escherichia coli strains isolated from a human and from poultry meat.

Funder

UC-Care

CPH Pig

Lundbeckfonden

Joint Programming Initiative on Antimicrobial Resistance

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02528-18

Reference33 articles.