Affiliation:
1. Division of Pediatric Infectious Diseases, Rhode Island Hospital, Providence, Rhode Island
Abstract
SUMMARY
The Centers for Disease Control and Prevention has identified immunization as the most important public health advance of the 20th century. The purpose of this article is to review the changes that have taken place in active immunization in the United States over the past decade. Since 1990, new vaccines have become available to prevent five infectious diseases: varicella, rotavirus, hepatitis A, Lyme disease, and Japanese encephalitis virus infection. Improved vaccines have been developed to prevent Haemophilus influenzae type b, pneumococcus, pertussis, rabies, and typhoid infections. Immunization strategies for the prevention of hepatitis B, measles, meningococcal infections, and poliomyelitis have changed as a result of the changing epidemiology of these diseases. Combination vaccines are being developed to facilitate the delivery of multiple antigens, and improved vaccines are under development for cholera, influenza, and meningococcal disease. Major advances in molecular biology have enabled scientists to devise new approaches to the development of vaccines against diseases ranging from respiratory viral to enteric bacterial infections that continue to plague the world's population.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Microbiology (medical),Public Health, Environmental and Occupational Health,General Immunology and Microbiology,Epidemiology
Reference378 articles.
1. A canarypox vector-expressing cytomegalovirus (CMV) glycoprotein B primes for antibody responses to a live attenuated CMV vaccine (Towne).;Adler S.;J. Infect. Dis.,1999
2. Immunity induced by primary human cytomegalovirus infection protects against secondary infection among women of childbearing age.;Adler S.;J. Infect. Dis.,1995
3. The changing epidemiology of hepatitis B in the United States.;Alter M. J.;JAMA.,1990
4. American Academy of Pediatrics
Arboviruses
2000 Red Book: Report of the Committee on Infectious Diseases
24th ed.
Pickering
L. K.
2000
170
175
American Academy of Pediatrics
Elk Grove Village Ill
5. American Academy of Pediatrics
Hepatitis B
2000 Red Book: Report of the Committee on Infectious Diseases
24th ed.
Pickering
L. K.
2000
289
302
American Academy of Pediatrics
Elk Grove Village Ill
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