Affiliation:
1. Department of Chemistry, Miranda House, University of Delhi,India
Abstract
:
The recent developments in the field of extracellular vesicles (EVs) point to
their potential use for predicting and treating neurodegenerative diseases. This review
focusses on the importance and latest advances in this field, especially with respect to
Alzheimer’s disease (AD). Increasing evidence shows that the progression of amyloidbeta
and tau brain pathology is correlated to the cognitive decline associated with AD.
Lot of experimental data suggests the involvement of EVs with these processes, for
instance EVs are known to circulate the misfolded proteins involved in AD. The currently
available information on the role of EVs in neurodegenerative disorder especially in AD
have also presented the knowledge gaps on which future research efforts should be
focused.
Publisher
Bentham Science Publishers Ltd.
Subject
Molecular Biology,Molecular Medicine,General Medicine,Biochemistry
Cited by
3 articles.
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