Mismatches in the Influenza A Virus RNA Panhandle Prevent Retinoic Acid-Inducible Gene I (RIG-I) Sensing by Impairing RNA/RIG-I Complex Formation
Author:
Affiliation:
1. Department of Microbiology and Molecular Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland
Abstract
Funder
Swiss National Science Foundation
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
Link
https://journals.asm.org/doi/pdf/10.1128/JVI.01671-15
Reference17 articles.
1. Master sensors of pathogenic RNA – RIG-I like receptors
2. Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates
3. Influenza A Virus Panhandle Structure Is Directly Involved in RIG-I Activation and Interferon Induction
4. Incoming RNA Virus Nucleocapsids Containing a 5′-Triphosphorylated Genome Activate RIG-I and Antiviral Signaling
5. Tacaribe arenavirus RNA synthesis in vitro is primer dependent and suggests an unusual model for the initiation of genome replication
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