Cytoplasm and Beyond: Dynamic Innate Immune Sensing of Influenza A Virus by RIG-I-Reference-Cited by-同舟云学术

Cytoplasm and Beyond: Dynamic Innate Immune Sensing of Influenza A Virus by RIG-I

Published:2019-04-15 Issue:8 Volume:93 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Liu GuanQun¹^ORCID,Zhou Yan¹^ORCID

Affiliation:

1. Vaccine and Infectious Disease Organization–International Vaccine Centre (VIDO-InterVac), University of Saskatchewan, Saskatoon, Saskatchewan, Canada

Abstract

Innate immune sensing of influenza A virus (IAV) requires retinoic acid-inducible gene I (RIG-I), a fundamental cytoplasmic RNA sensor. How RIG-I’s cytoplasmic localization reconciles with the nuclear replication nature of IAV is poorly understood.

Funder

Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada

Public Health Agency of Canada

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.02299-18

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