Barrier to Resistance of Dolutegravir in Two-Drug Combinations-Reference-Cited by-同舟云学术

Barrier to Resistance of Dolutegravir in Two-Drug Combinations

Published:2019-03 Issue:3 Volume:63 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Yoshinaga Tomokazu¹,Miki Shigeru¹,Kawauchi-Miki Shinobu¹,Seki Takahiro¹,Fujiwara Tamio²

Affiliation:

1. Drug Discovery & Disease Research Laboratory, Shionogi & Co., Ltd., Osaka, Japan

2. Global Development, Shionogi & Co., Ltd., Osaka, Japan

Abstract

A major concern when using two-drug anti-HIV regimens is the risk of viral resistance. However, no techniques to evaluate the barrier to resistance of two-drug combinations in vitro have been reported.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02104-18

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