Interactions of 1263W94 with Other Antiviral Agents in Inhibition of Human Cytomegalovirus Replication-Reference-Cited by-同舟云学术

Interactions of 1263W94 with Other Antiviral Agents in Inhibition of Human Cytomegalovirus Replication

Published:2003-04 Issue:4 Volume:47 Page:1468-1471
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Selleseth Dean W.¹,Talarico Christine L.¹,Miller Teresa¹,Lutz Michael W.¹,Biron Karen K.¹,Harvey Robert J.¹

Affiliation:

1. GlaxoSmithKline, Research Triangle Park, North Carolina 27709

Abstract

ABSTRACT Inhibition of human cytomegalovirus (HCMV) by 1263W94 was additive dosewise in combination with ganciclovir, acyclovir, and foscarnet. None of the commonly used anti-human immunodeficiency virus agents antagonized the inhibition of HCMV by 1263W94. The data were analyzed by a modified isobologram procedure that measures the strength and statistical significance of drug interactions.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.47.4.1468-1471.2003

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