Coculturing Bacteria Leads to Reduced Phenotypic Heterogeneities-Reference-Cited by-同舟云学术

Coculturing Bacteria Leads to Reduced Phenotypic Heterogeneities

Published:2019-04-15 Issue:8 Volume:85 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Heyse Jasmine¹^ORCID,Buysschaert Benjamin¹,Props Ruben¹,Rubbens Peter²^ORCID,Skirtach Andre G.³,Waegeman Willem²,Boon Nico¹

Affiliation:

1. Center for Microbial Ecology and Technology, Department of Biochemical and Microbial Technology, Ghent University, Ghent, Belgium

2. KERMIT, Department of Data Analysis and Mathematical Modeling, Ghent University, Ghent, Belgium

3. Nano-Bio-Technology Group, Department of Biotechnology, Ghent University, Ghent, Belgium

Abstract

Laboratory studies have shown the impact of phenotypic heterogeneity on the survival and functionality of isogenic populations. Because phenotypic heterogeneity plays an important role in pathogenicity and virulence, antibiotic resistance, biotechnological applications, and ecosystem properties, it is crucial to understand its influencing factors. An unanswered question is whether bacteria in mixed communities influence the phenotypic heterogeneity of their community partners. We found that coculturing bacteria leads to a reduction in their individual phenotypic heterogeneities, which led us to the hypothesis that the individual phenotypic diversity of a taxon is dependent on the community composition.

Funder

Fonds Wetenschappelijk Onderzoek

Agentschap voor Innovatie door Wetenschap en Technologie

Bijzonder Onderzoeksfonds

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.02814-18

Reference67 articles.

1. Non-genetic individuality: chance in the single cell